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April 10, 2024 - Page 2 of 3 - The Dermatology Digest
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AD Pipeline Watch: Sitryx Advances SYX-5219 to the Clinic

Sitryx Therapeutics plans to advance SYX-5219, an oral, targeted, disease-modifying anti-inflammatory therapy that targets pyruvate kinase M2 (PKM2), to the clinic. Modulation of PKM2 alters B and T lymphocyte function and represents a novel therapeutic target with the potential to rebalance the immune system, normalize immune cell function and drive sustained disease remission in AD. […]