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August 5, 2024 - Page 2 of 2 - The Dermatology Digest
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Can Cyclo (L-Pro-L-Tyr) Safely Fade Hyperpigmentation?

A tyrosinase inhibitor from Corynebacterium tuberculostearicum (C. tuberculostearicum), a bacterium commonly found on human skin, may help safely treat hyperpigmentation. After screening over 100 skin-derived bacteria, the researchers identified C. tuberculostearicum as a producer of a potent tyrosinase-inactivating compound. Their assays utilized tyrosinase from the mushroom Agaricus bisporus to confirm inhibition. Subsequent experiments pinpointed the active compound as cyclo (L-Pro-L-Tyr). […]