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February 20, 2025 - Page 2 of 3 - The Dermatology Digest
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First Patient Dosed in Phase 1b Trial of VYNE’s BET Inhibitor in Moderate-to-severe PsO

The first subject has been dosed in a Phase 1b trial evaluating VYNE Therapeutics Inc.’s VYN202 in moderate-to-severe plaque psoriasis. VYN202 is an oral small molecule BD2-selective bromodomain and extra-terminal domain (BET) inhibitor that is being developed for the treatment of immune-mediated diseases. The Phase 1b trial is a randomized, double-blind, placebo-controlled trial evaluating the safety, […]