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Psoriasis Archives - The Dermatology Digest
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Phase 3 Data: “Game-changing” Oral IL-23 Blocker Shows Efficacy and Safety in PsO

Icotrokinra, a first-in-class targeted oral peptide that selectively blocks interleukin (IL)-23, demonstrated significantly higher rates of skin clearance and a favorable safety profile in adults and adolescents with moderate-to-severe plaque psoriasis, according to the first Phase 3 study, which was presented at the 2025 American Academy of Dermatology’s annual meeting in Orlando, FL. Protagonist Therapeutics […]